Sunday, April 3, 2011

Tetanus

OVERVIEW
Clostridium tetani—an obligate, anaerobic, spore-forming, gram-positive rod found in soil and as part of the normal bacterial flora of the intestinal tract of mammals with a predilection for contaminated, necrotic, anaerobic wounds (puncture, surgery, lacerations, burns, frostbite, open fractures, abrasions)
Germi-nating spores—in wounds produce potent exotoxin tetanospasmin (tetanus toxin); resistant to disinfectants and to the effects of environmental exposure
Found worldwide, especially in the tropics.

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