Papillomatosis

OVERVIEW
Papillomaviruses (PVs)—group of nonenveloped, double-stranded DNA viruses that induce proliferative cutaneous tumors in cats and dogs and mucosal tumors in dogs; each is host and fairly site-specific, with characteristic clinical and microscopic changes in infected tissues.
Tumors—papillomas, warts, or verrucae; generally benign; spontaneously regress; rarely may undergo conversion to SCC
Lesions—often multiple, well demarcated, and exophytic; sometimes hyperkeratotic plaques or with papules; may be deeply pigmented (black or brown), pink, tan, or white
Infection—inoculation through breaks in the epidermis or mucosal epithelium; iatrogenic transmission through use of contaminated instruments possible